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A Guide to Interpreting Your Genetic Risk Score for Diabetes

04 Sep 2025 by Eleanna O. De Filippis, M.D., Ph.D.

A Guide to Interpreting Your Genetic Risk Score for Diabetes

Interpreting your genetic risk score for diabetes is a crucial step in understanding your likelihood of developing the condition. While genetics only play a part in the risk, having a comprehensive understanding of your genetic predisposition can help you take proactive steps towards reducing your risk.

When you receive your genetic risk score, you'll typically get a numerical value that indicates your likelihood of developing diabetes. This score is usually calculated based on multiple genetic variants associated with an increased risk of developing the condition. The score can range from 0 to 100, with higher scores indicating a greater risk.

Understanding Your Genetic Risk Score

Your genetic risk score is not a prediction, but rather a probability. It indicates the likelihood that you will develop diabetes based on your genetic makeup. The score is usually divided into different risk categories, such as low, moderate, or high. A Beginner S Guide To Continuous Glucose Monitors Cgm

  • Low risk: 0-20
  • Moderate risk: 21-50
  • High risk: 51-100

Factors That Influence Your Genetic Risk Score

While genetics play a significant role in your risk, other factors can also influence your score. These include:

  • Family history: If you have a first-degree relative (parent or sibling) with diabetes, your risk is higher.
  • Age: The risk of developing diabetes increases with age, especially after 45.
  • Body mass index (BMI): A higher BMI increases your risk of developing diabetes.
  • Ethnicity: Certain ethnic groups, such as African Americans, Hispanics/Latinos, and American Indians, are at higher risk of developing diabetes.

What Your Genetic Risk Score Means for You

Receiving your genetic risk score can be a mixed bag of emotions. While it can provide valuable insights into your risk, it's essential to remember that genetics is only one factor. Mastering Your Fasting Blood Sugar Tips To Get An Accurate Reading Every Time

  • Low risk: If you have a low risk score, you can breathe a sigh of relief. However, it's still essential to maintain a healthy lifestyle, including a balanced diet and regular exercise.
  • Moderate risk: If you have a moderate risk score, you'll need to take proactive steps to reduce your risk. This may include making lifestyle changes, such as losing weight or increasing physical activity.
  • High risk: If you have a high risk score, it's essential to work closely with your healthcare provider to develop a personalized plan to reduce your risk.

Reducing Your Risk

While genetics can't be changed, there are steps you can take to reduce your risk of developing diabetes.

  • Maintain a healthy weight: Losing weight, if you're overweight or obese, can significantly reduce your risk.
  • Exercise regularly: Engaging in regular physical activity, such as brisk walking or cycling, can help lower your risk.
  • Eat a healthy diet: Focus on whole, unprocessed foods, such as vegetables, fruits, and whole grains.
  • Manage stress: Chronic stress can increase your risk of developing diabetes. Engage in stress-reducing activities, such as yoga or meditation.

In conclusion, interpreting your genetic risk score for diabetes is just the first step. While genetics play a role in your risk, there are many other factors at play. By understanding your score and taking proactive steps to reduce your risk, you can take control of your health and reduce your likelihood of developing diabetes. What Are Normal Blood Sugar Levels By Age The Definitive Chart

References and Further Reading