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A Guide to LADA (Latent Autoimmune Diabetes in Adults)

04 Sep 2025 by Lori R. Roust, M.D.

A Guide to LADA (Latent Autoimmune Diabetes in Adults)

LADA, or Latent Autoimmune Diabetes in Adults, is a form of diabetes that can be challenging to diagnose and manage. It is characterized by the presence of autoantibodies, which are proteins that the immune system produces in response to the presence of foreign substances. In the case of LADA, these autoantibodies target and damage the cells in the pancreas that produce insulin, leading to a decline in insulin production and eventually, high blood sugar levels.

What is LADA?

LADA is a type of autoimmune diabetes that is distinct from type 1 and type 2 diabetes. While type 1 diabetes is typically diagnosed in children and young adults, LADA is diagnosed in adults, often after the age of 30. Type 2 diabetes, on the other hand, is a form of diabetes that is associated with insulin resistance, which is a condition in which the body's cells become less responsive to insulin.

Symptoms of LADA

The symptoms of LADA can be similar to those of type 2 diabetes, and may include:

  • Increased thirst and urination
  • Fatigue
  • Blurred vision
  • Cuts or wounds that are slow to heal
  • Tingling or numbness in the hands and feet

However, some people with LADA may not experience any noticeable symptoms at all.

Diagnosis of LADA

Diagnosing LADA can be challenging, as the symptoms are often similar to those of type 2 diabetes. A diagnosis is typically made through a combination of physical examination, medical history, and laboratory tests. These tests may include: Decoding Your Blood Glucose Test A Simple Guide To Mg Dl Vs Mmol L

  • Fasting blood glucose test: This test measures the level of glucose in the blood after an overnight fast.
  • Oral glucose tolerance test: This test measures the level of glucose in the blood after consuming a sugary drink.
  • Autoantibody tests: These tests measure the presence of autoantibodies in the blood, which can indicate the presence of an autoimmune response.

Treatment of LADA

The treatment of LADA typically involves lifestyle changes, such as:

  • Dietary modifications: Eating a healthy diet that is low in sugar and refined carbohydrates can help to manage blood sugar levels.
  • Exercise: Regular exercise, such as walking or strength training, can help to improve insulin sensitivity.
  • Medications: Oral medications, such as metformin, or injectable medications, such as insulin, may be prescribed to help manage blood sugar levels.

Complications of LADA

If left untreated, LADA can lead to a number of complications, including:

  • Nerve damage
  • Kidney damage
  • Blindness
  • Amputation

It is essential to work with a healthcare provider to manage LADA and prevent these complications.

Living with LADA

Living with LADA requires a combination of lifestyle changes and medical management. It is essential to work with a healthcare provider to develop a treatment plan that meets individual needs. This may include: Fasting Normal Blood Sugar The Numbers To Know

  • Monitoring blood sugar levels regularly
  • Adjusting medications as needed
  • Making dietary changes
  • Engaging in regular exercise

By working with a healthcare provider and making lifestyle changes, it is possible to manage LADA and prevent complications. Blood Sugar For Beginners Your Guide To Testing Levels And Control

Conclusion

LADA is a form of diabetes that can be challenging to diagnose and manage. However, with the right treatment and lifestyle changes, it is possible to manage the condition and prevent complications. If you are experiencing symptoms of LADA, it is essential to work with a healthcare provider to develop a treatment plan that meets your individual needs.

References and Further Reading