Select Your Country/Region

United States English
中国(大陆) 简体中文
España Español
CIS Русский
日本 日本語
Deutschland Deutsch
Italia Italian
Portugal Português
Philippines Philippines
Europe English
Global (Other country or region) English
All Where to Buy About Chuwi Contact Us Blogs Company News Video Center

Hypoglycemia Explained: The Causes and Symptoms of Low Blood Sugar

04 Sep 2025 by Sagar Dugani, M.D., Ph.D.

Hypoglycemia Explained: The Causes and Symptoms of Low Blood Sugar

Have you ever felt shaky, lightheaded, or suddenly ravenous, even after a recent meal? You might be experiencing hypoglycemia, also known as low blood sugar. Understanding hypoglycemia, its causes, symptoms, and management strategies, is crucial for anyone, especially those with diabetes. This comprehensive guide will break down everything you need to know about low blood sugar, helping you recognize, address, and prevent this condition. The Perfect Blood Sugar Diet A 7 Day Meal Plan To Stabilize Glucose

What is Hypoglycemia?

Hypoglycemia occurs when the level of glucose (sugar) in your blood drops below normal. Glucose is your body's primary source of energy, fueling everything from your brain to your muscles. When blood glucose levels fall too low, your body struggles to function correctly, leading to a variety of symptoms. The threshold for low blood sugar varies, but generally, it's considered hypoglycemia when your blood glucose level drops below 70 mg/dL (3.9 mmol/L).

While commonly associated with diabetes and its treatments, hypoglycemia can also occur in people without diabetes, although it's less frequent. In such cases, it's often called non-diabetic hypoglycemia.

Causes of Hypoglycemia: Why Does Blood Sugar Drop?

Several factors can contribute to low blood sugar. The causes differ depending on whether you have diabetes or not. Blood Glucose Meter 101 Choosing A Device And Using Test Strips

Hypoglycemia in People with Diabetes:

  • Insulin Overdose: This is the most common cause. Taking too much insulin can cause your blood glucose to drop significantly.
  • Skipping or Delaying Meals: If you take insulin or other diabetes medications, missing or delaying meals disrupts the balance between medication and food intake.
  • Intense Exercise: Physical activity uses glucose for energy. If you don't adjust your medication or food intake before, during, or after exercise, you may experience hypoglycemia.
  • Alcohol Consumption: Alcohol can interfere with the liver's ability to release glucose into the bloodstream, particularly if consumed on an empty stomach.
  • Certain Medications: Some diabetes medications, especially sulfonylureas, can increase the risk of low blood sugar.
  • Kidney or Liver Problems: These organs play a crucial role in regulating blood glucose. Impaired function can lead to hypoglycemia.

Hypoglycemia in People Without Diabetes (Non-Diabetic Hypoglycemia):

  • Reactive Hypoglycemia: This occurs a few hours after eating, especially after consuming meals high in carbohydrates. It’s caused by an overproduction of insulin in response to the rapid rise in blood glucose.
  • Fasting Hypoglycemia: This happens after a prolonged period without eating. Potential causes include:
    • Tumors: Rare insulin-secreting tumors (insulinomas).
    • Severe Liver Disease: Compromises the liver's ability to store and release glucose.
    • Kidney Failure: Can affect glucose metabolism.
    • Adrenal Gland Disorders: The adrenal gland produces hormones that help regulate blood glucose.
    • Certain Medications: Some medications, like quinine (used to treat malaria), can lower blood sugar.
  • Post-Gastric Bypass Surgery: Changes in digestion can sometimes lead to hypoglycemia.
  • Hormone Deficiencies: Problems with growth hormone, cortisol, or glucagon can contribute.
  • Sepsis: Severe infections can disrupt glucose regulation.

Symptoms of Hypoglycemia: Recognizing the Signs

Recognizing the symptoms of low blood sugar is crucial for prompt treatment. Symptoms can vary from mild to severe and may differ from person to person. Here's a breakdown of common hypoglycemia symptoms:

Mild to Moderate Symptoms:

  • Shakiness or Trembling: A common early sign.
  • Sweating: Often cold and clammy.
  • Dizziness or Lightheadedness: Feeling unsteady or faint.
  • Hunger: An intense craving for food.
  • Irritability or Anxiety: Feeling edgy or easily agitated.
  • Confusion: Difficulty thinking clearly or concentrating.
  • Rapid Heartbeat (Palpitations): Feeling like your heart is racing.
  • Pale Skin: Loss of color in the face.
  • Blurred Vision: Difficulty seeing clearly.
  • Weakness or Fatigue: Feeling tired and lacking energy.
  • Headache: A throbbing or dull pain.

Severe Symptoms (Require Immediate Medical Attention):

  • Seizures: Uncontrolled muscle contractions and loss of consciousness.
  • Loss of Consciousness: Passing out or being unresponsive.
  • Coma: A prolonged state of unconsciousness.

It's important to note that some people with diabetes may experience hypoglycemia unawareness, where they don't feel the warning signs of low blood sugar until it becomes severe. This is more common in people who have had diabetes for a long time or who frequently experience hypoglycemia. Regular blood glucose monitoring is crucial in these cases.

Diagnosing Hypoglycemia

Diagnosing hypoglycemia typically involves:

  • Blood Glucose Testing: Using a blood glucose meter or continuous glucose monitor (CGM) to measure blood glucose levels at the time of symptoms.
  • Medical History and Physical Examination: A healthcare provider will ask about your medical history, medications, and lifestyle to identify potential causes.
  • Oral Glucose Tolerance Test (OGTT): In some cases, particularly to diagnose reactive hypoglycemia, an OGTT may be performed. This involves drinking a sugary solution and having your blood glucose levels measured at intervals over several hours.
  • Fasting Blood Glucose Test: For suspected fasting hypoglycemia, blood glucose levels are measured after a period of fasting.
  • Other Tests: Depending on the suspected cause, additional tests may be ordered, such as tests to evaluate liver, kidney, or adrenal gland function, or imaging studies to look for tumors.

Treating Hypoglycemia: Immediate Action and Long-Term Management

The primary goal of hypoglycemia treatment is to rapidly raise blood glucose levels back to normal.

Immediate Treatment:

  • The 15-15 Rule: If you experience symptoms of hypoglycemia and can check your blood glucose, follow the 15-15 rule:
    • Consume 15 grams of fast-acting carbohydrates. Examples include:
      • Glucose tablets
      • 4 ounces (120 ml) of fruit juice (not diet)
      • 4 ounces (120 ml) of regular (not diet) soda
      • 1 tablespoon of honey or sugar
    • Wait 15 minutes and recheck your blood glucose.
    • If your blood glucose is still below 70 mg/dL (3.9 mmol/L), repeat the 15-15 rule.
    • Once your blood glucose is above 70 mg/dL, eat a meal or snack containing both carbohydrates and protein to prevent another drop.
  • Glucagon: If you are unable to swallow or are unconscious, a glucagon injection may be needed. Glucagon is a hormone that stimulates the liver to release stored glucose into the bloodstream. People at risk of severe hypoglycemia should have a glucagon kit available and family members should be trained on how to administer it.
  • Emergency Medical Assistance: In cases of severe hypoglycemia with loss of consciousness, call emergency services immediately.

Long-Term Management:

Long-term management of hypoglycemia involves addressing the underlying cause and implementing strategies to prevent future episodes. This includes: Feeling Tired And Thirsty It Could Be Your Blood Glucose Levels

  • For People with Diabetes:
    • Medication Adjustments: Work with your healthcare provider to adjust your insulin or other diabetes medication dosage.
    • Meal Planning: Eat regular meals and snacks, and ensure that meals contain a balance of carbohydrates, protein, and fat.
    • Blood Glucose Monitoring: Regularly monitor your blood glucose levels, especially before meals, before and after exercise, and at bedtime.
    • Exercise Planning: Adjust your medication or food intake before, during, and after exercise to prevent low blood sugar.
    • Alcohol Awareness: Be aware of the effects of alcohol on blood glucose levels and consume alcohol in moderation, with food.
    • Continuous Glucose Monitoring (CGM): A CGM can help you track your blood glucose levels in real-time and identify trends. Some CGMs can also alert you when your blood glucose is falling too low.
  • For People Without Diabetes:
    • Dietary Changes: For reactive hypoglycemia, avoiding sugary drinks and high-carbohydrate meals can help. Eating smaller, more frequent meals and including protein and fiber with each meal can also help stabilize blood glucose levels.
    • Treating Underlying Medical Conditions: Address any underlying medical conditions that may be contributing to hypoglycemia, such as liver or kidney problems, adrenal gland disorders, or tumors.
    • Medication Review: Review your medications with your healthcare provider to identify any drugs that may be causing hypoglycemia.

Preventing Hypoglycemia: Tips for Staying Safe

Preventing low blood sugar is key to maintaining overall health and well-being. Here are some practical tips:

  • Regular Monitoring: Consistently check your blood sugar levels, especially if you are diabetic or prone to hypoglycemic episodes.
  • Consistent Meal Schedule: Avoid skipping meals and maintain a steady eating schedule, with healthy snacks when needed.
  • Smart Snacking: Keep healthy snacks handy, especially when you are engaging in physical activity or traveling.
  • Communicate with your doctor: If you're experiencing frequent hypoglycemia, promptly discuss it with your doctor.

The Importance of Understanding Hypoglycemia

Hypoglycemia is a serious condition that requires understanding and proactive management. By recognizing the symptoms, identifying the underlying causes, and implementing appropriate treatment and prevention strategies, you can effectively manage low blood sugar and maintain your health and well-being. Whether you have diabetes or not, knowledge about hypoglycemia empowers you to take control of your health and respond effectively to low blood sugar emergencies. Regular monitoring, a healthy diet, and open communication with your healthcare provider are essential for preventing and managing hypoglycemia effectively.


Key Takeaways:

  • Hypoglycemia is low blood sugar.
  • Recognizing symptoms is crucial.
  • Causes differ for diabetics and non-diabetics.
  • Treatment involves raising blood sugar levels quickly.
  • Long-term management focuses on prevention.

References and Further Reading