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When a "Diabetic Foot Ulcer" is Actually Peripheral Artery Disease

04 Sep 2025 by Maria L. Collazo-Clavell, M.D.

When a "Diabetic Foot Ulcer" is Actually Peripheral Artery Disease

When a diabetic foot ulcer is diagnosed, the primary concern is usually the risk of infection and potential amputation. However, in some cases, a foot ulcer may be a symptom of an underlying condition that requires immediate attention – Peripheral Artery Disease (PAD). In this article, we'll explore the link between diabetic foot ulcers and PAD, and discuss how this often-overlooked connection can impact treatment and prognosis. The Prediabetes Diet 20 Blood Sugar Friendly Meals To Try This Week

Peripheral Artery Disease (PAD) is a condition in which the arteries that supply blood to the limbs (arms and legs) become narrowed or blocked, reducing blood flow to the extremities. In diabetic patients, PAD is often a complication of long-standing uncontrolled diabetes, which can lead to atherosclerosis (the buildup of plaque in the arteries) and subsequent reduced blood flow to the legs and feet. How To Critically Evaluate Health News And Medical Research

A diabetic foot ulcer is a common complication of PAD, but not all foot ulcers are PAD-related. However, in patients with a history of diabetes, peripheral neuropathy, and foot ulcers, PAD should always be considered a potential underlying cause.

Recognizing the Signs of PAD

While a diabetic foot ulcer is the most obvious symptom, there are other signs and symptoms that may indicate the presence of PAD. These include: Continuous Glucose Monitor Cgm Vs Meter Which Is Right For You

  • Pain or cramping in the legs or feet when walking or exercising, which can be a sign of inadequate blood flow to the muscles
  • Poor wound healing in the legs or feet, which can be a sign of reduced blood flow to the affected area
  • Changes in skin color or temperature in the legs or feet, which can be a sign of reduced blood flow
  • Weak or absent pulses in the legs or feet, which can be a sign of PAD

Diagnosing PAD in Diabetic Patients

Diagnosing PAD in diabetic patients typically involves a combination of clinical evaluation, imaging studies, and laboratory tests. These may include:

  • Ankle-brachial index (ABI): a non-invasive test that measures blood pressure in the ankles and arms to determine blood flow to the legs
  • Segmental Doppler studies: a non-invasive test that uses ultrasound to measure blood flow to specific areas of the legs
  • Arterial imaging studies: such as CT or MRI scans to visualize the arteries and identify blockages or narrowing

Treating PAD in Diabetic Patients

Treatment of PAD in diabetic patients typically involves a combination of lifestyle modifications, medication, and interventional procedures. These may include:

  • Smoking cessation: a critical step in reducing the risk of PAD and its complications
  • Exercise: regular exercise, such as walking, can help improve blood flow to the legs and reduce the risk of PAD
  • Medication: medications such as statins and aspirin can help reduce inflammation and prevent blood clots
  • Interventional procedures: such as angioplasty or stenting may be necessary to restore blood flow to the affected area

Conclusion

In conclusion, a diabetic foot ulcer can be a symptom of Peripheral Artery Disease (PAD), a condition that requires immediate attention. Recognizing the signs and symptoms of PAD, diagnosing the condition, and treating it promptly can help prevent complications and improve outcomes. By working closely with a healthcare provider, diabetic patients can reduce their risk of PAD and its complications, and maintain optimal health.

References and Further Reading