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Why Humans Are Relatively Poor at Ketosis Compared to Other Mammals

04 Sep 2025 by Marc R. Matthews, M.D.

Why Humans Are Relatively Poor at Ketosis Compared to Other Mammals

Ketosis is a metabolic state in which the body burns fat for energy instead of carbohydrates, producing ketones in the process. This state is commonly achieved through a diet low in carbohydrates and high in fat, known as a ketogenic diet. While humans can achieve ketosis, the process is often more challenging for us compared to other mammals. There are several reasons why humans are relatively poor at ketosis compared to other mammals.

Evolutionary Factors

One reason humans struggle with ketosis is due to our evolutionary history. Humans evolved to be primarily obligate carnivores, meaning we were designed to eat meat as our main source of sustenance. However, our diet has changed significantly over the years, and we now often rely heavily on carbohydrates for energy. This has made it more difficult for our bodies to adapt to a ketogenic diet.

Body Composition

Humans have a relatively high percentage of body fat compared to other mammals, which can make it more difficult to achieve ketosis. When we consume carbohydrates, they are quickly converted to glucose, which is then used for energy. This means that our bodies are not as efficient at burning fat for energy as some other mammals. What Does A Normal Blood Sugar Level Look Like By Age

Insulin Resistance

Insulin resistance is a condition in which the body becomes less responsive to insulin, leading to higher blood sugar levels. This can make it more challenging to achieve ketosis, as the body is not able to efficiently use glucose for energy. Insulin resistance is a common problem in modern society, particularly in developed countries.

Dietary Changes

The way humans consume food has changed significantly over the years. We often consume high amounts of carbohydrates and added sugars, which can make it more difficult to achieve ketosis. Additionally, many of us do not eat a diet that is high in healthy fats, which are essential for achieving ketosis.

Comparison to Other Mammals

Other mammals, such as dogs and cats, are often more efficient at ketosis due to their evolutionary history and diet. These animals have evolved to be primarily carnivores, and their bodies are designed to burn fat for energy. For example, dogs can achieve ketosis quickly and easily, and their bodies are highly efficient at burning fat for energy. In The Prediabetes Range How To Manage Blood Sugar And Reverse It

Conclusion

In conclusion, humans are relatively poor at ketosis compared to other mammals due to a combination of evolutionary factors, body composition, insulin resistance, dietary changes, and comparison to other mammals. While it is possible for humans to achieve ketosis, it often requires a significant amount of effort and dedication. By understanding the reasons behind our poor ability to achieve ketosis, we can take steps to improve our metabolic health and achieve a more efficient state of energy production. The Complete Blood Sugar Diet Plan For Beginners

References and Further Reading